龙飞副教授个人简介
1. 简介(Introductions)
龙飞,广州医科大学广州霍夫曼免疫研究所副研究员。2008年博士毕业于华中农业大学生命科学技术学院;2009年至2014年历任中国科学院广州生物医药与健康研究院副研究员、中国科学院南海生物医药科技产业中心研发部主任;2014年至今,任广州医科大学广州霍夫曼免疫研究所副研究员、党支部书记。2012年入选佛山市南海区高层次人才,2013年入选中国科学院青年创新促进会会员。主持科研项目9项,发表论文15篇(其中SCI论文9篇),参编专著2部,申请国家发明专利10项(获授权6项)。
Dr. Long is an associate researcher in SFHI at Guangzhou Medical University. He received his Ph.D. degree in Microbiology from Huazhong agricultural University in 2008. From 2009 to 2014, he served as an associate researcher at Guangzhou Institutes of Biomedicine and Health, and a director of R&D at CAS-FS Biotech and Pharmaceutical Center. Afterwards, he joined Guangzhou Medical University as associate researcher.
Dr. Long is a recipient of the “High-level talents in Nanhai, Foshan” (2012), and a member of the “Youth Innovation Promotion Association, CAS” (2013). He has presided nine research projects, published 15 papers (9 papers were SCI indexed), and participated in compiling 2 books. He has also taken part in applying 10 patents and 6 patents have been issued.
2. 主要研究方向(Research interests)
主要从事呼吸道相关疾病新型生物标志物的发掘及临床应用的研究。通过建立蛋白芯片和质谱等高通量检测平台,对不同来源生物样本进行标志物的筛选、鉴定,并探索生物标志物在疾病诊断、治疗、以及疗效监测等方面的临床应用。
The research interest of Dr. Long is the new biomarkers of respiratory diseases and clinical application. Work in progress focuses on the development of high-throughput proteome detection platform, identification of new biomarkers, and exploration of the clinical application in disease diagnosis, treatment, and efficacy monitoring.
3. 代表性论文(Selected publications)
1)Qin R+, Long F+, Xiao X, Xiao J, Zheng Z, Feng M, Huang R, Peng T*, Li J*. Sputum Autoantibodies Are More Relevant in Autoimmune Responses in Asthma than Are Serum Autoantibodies. Allergy Asthma Immunol Res, 2019, 11(3):406-421.
2) ZY LIANG+, F LONG+, FY WANG+, YQ YANG, J XIAO, KM DENG, WL GU, LQ ZHOU, JX XIE, WH JIAN, X CHEN, M JIANG, JP ZHENG, T PENG*, RC CHEN*. Identification of clinically relevant subgroups of COPD based on airway and circulating autoantibody profiles. Mol Med Rep, 2019, 20:2882-2892.
3)Jing xiao+, Fei Long+, Tao peng+, Longbo Hu, Hua Cai, Ren Chen*, Wenli Chen*. Development and potential application of a simultaneous multiplex assay of Golgi protein 73 and alpha-fetoprotein for hepatocellular carcinoma diagnosis. Eur Rev Med Pharmacol Sci, 2019, 23:3302-3310.
4)Li J+, Ma C+, Long F+, Yang D, Liu X, Hu Y, Wu C, Wang B, Wang M, Chen Y, Liu G, Moynagh PN, Zhou J, Peng T*, Yang S*. Parkin Impairs Antiviral Immunity by Suppressing the Mitochondrial Reactive Oxygen Species-Nlrp3 Axis and Antiviral Inflammation. iScience, 2019, 16:468-484.
5)Zhou L, Chen D, Huang XM, Long F, Cai H, Yao WX, Chen ZC, Liao ZJ, Deng ZZ, Tan S, Shan YL, Cai W, Wang YG, Yang RH, Jiang N, Peng T, Hong MF, Lu ZQ. Wnt5a Promotes Cortical Neuron Survival by Inhibiting Cell-Cycle Activation. Front Cell Neurosci, 2017, 11:281.
6)Zhu QC, Wang Y, Liu YP, Zhang RQ, Li X, Su WH, Long F, Luo XD, Peng T. Inhibition of enterovirus 71 replication by chrysosplenetin and penduletin. Eur J Pharm Sci, 2011, 44(3):392-398.
7)Xian-ming Shi*, Fei Long, and Biao Suo. Molecular methods for the detection and characterization of foodborne pathogens. Pure Appl Chem, 2010, 82(1):69-79
8)Fei Long, Xin-na Zhu, Zhong-ming Zhang and Xian-ming Shi*. Development of a Quantitative PCR Method Using a Live Bacterium as InternalControl for the Detection of Listeria monocytogenes. Diagn Microbiol Infect Dis, 2008, 62(4): 374-381
9)Xinna Zhu, Fei Long, Yonghui Chen, Susanne Knøchel, Qunxin She, and Xianming Shi*. A putative ABC transporter is involved in negative regulation of biofilm formation by Listeria monocytogenes. Appl Environ Microbiol, 2008, 74(24):7675-7683